It has Malcolm's dad in it, which is usually all you need to tell people to make them watch it
Malcolm's Dad! (from Malcolm in the Middle). I love him and Malcolm's mum.
The plot is that Malcolm's dad is a chemistry teacher who secretly sets up a meth lab with a slacker who used to be his student and gets into wacky scrapes.
The two things I like best about it are that Malcolm's Dad is adorable, and also that he Wins by using Science Knowledge every week. Well, 'wins' is a bit strong: survives. Apparently the actor - I must use his real name, Bryan Cranston - won an Emmy for the role.
So, surprisingly highly recommended.